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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN1 All Species: 9.7
Human Site: S575 Identified Species: 16.41
UniProt: Q16512 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16512 NP_002732.3 942 103932 S575 R D P P S S P S S L S S P I Q
Chimpanzee Pan troglodytes XP_512443 1169 127241 S802 R D P P S S P S S L S S P L Q
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 P627 M T P P P K P P R L Y L P Q E
Dog Lupus familis XP_542019 1076 118222 S708 L G P P S S P S S L S S P I Q
Cat Felis silvestris
Mouse Mus musculus P70268 946 104392 C578 P G L P S T S C S L S S P T H
Rat Rattus norvegicus Q63433 946 104449 C578 A G L P S T S C S L S S P T H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 F615 P P K P P R L F L P L E P V A
Chicken Gallus gallus XP_422357 1013 114806 E599 L D F E L E P E P P P A P P R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689331 948 107057 P584 E V T D I S T P E R Q P S T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138 L301 R P G K C S L L D F N F I K V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133 S374 K V P G G T L S I H D F T F M
Sea Urchin Strong. purpuratus XP_787090 799 90414 P435 V S S P L T P P A A R S S P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500 N760 T N P F R D M N S E T F Q I E
Red Bread Mold Neurospora crassa P87253 1142 127954 A733 K Y N P A D Y A N I D A Y S S
Conservation
Percent
Protein Identity: 100 79.3 38.7 83 N.A. 91.6 91.9 N.A. 42.2 57.6 N.A. 66.7 N.A. 29 N.A. 27.8 48.5
Protein Similarity: 100 79.9 52.6 84.3 N.A. 94.7 94.6 N.A. 56.1 72.1 N.A. 79.5 N.A. 42.8 N.A. 43.4 61.7
P-Site Identity: 100 93.3 33.3 86.6 N.A. 46.6 46.6 N.A. 13.3 20 N.A. 6.6 N.A. 13.3 N.A. 13.3 20
P-Site Similarity: 100 100 40 86.6 N.A. 53.3 53.3 N.A. 20 33.3 N.A. 13.3 N.A. 20 N.A. 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.8 28.3
Protein Similarity: N.A. N.A. N.A. N.A. 44.4 45.1
P-Site Identity: N.A. N.A. N.A. N.A. 20 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 0 0 8 8 8 0 15 0 0 8 % A
% Cys: 0 0 0 0 8 0 0 15 0 0 0 0 0 0 0 % C
% Asp: 0 22 0 8 0 15 0 0 8 0 15 0 0 0 0 % D
% Glu: 8 0 0 8 0 8 0 8 8 8 0 8 0 0 22 % E
% Phe: 0 0 8 8 0 0 0 8 0 8 0 22 0 8 0 % F
% Gly: 0 22 8 8 8 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 15 % H
% Ile: 0 0 0 0 8 0 0 0 8 8 0 0 8 22 0 % I
% Lys: 15 0 8 8 0 8 0 0 0 0 0 0 0 8 0 % K
% Leu: 15 0 15 0 15 0 22 8 8 43 8 8 0 8 0 % L
% Met: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % M
% Asn: 0 8 8 0 0 0 0 8 8 0 8 0 0 0 0 % N
% Pro: 15 15 43 65 15 0 43 22 8 15 8 8 58 15 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 0 8 8 22 % Q
% Arg: 22 0 0 0 8 8 0 0 8 8 8 0 0 0 8 % R
% Ser: 0 8 8 0 36 36 15 29 43 0 36 43 15 8 8 % S
% Thr: 8 8 8 0 0 29 8 0 0 0 8 0 8 22 0 % T
% Val: 8 15 0 0 0 0 0 0 0 0 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 8 0 0 0 8 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _